ANOMALIES ASSOCIATED WITH MULLERIAN DUCT.
Anomalies associated with MULLERIAN DUCT
- MULLERIAN AGENESIS: various reproductive structures like fallopian tubes ,uterus ,cervix and upper 2/3rd of vagina 👉 not formed.
- lower 1/3rd of vagina 👉formed by urinogenital sinus👉leading to formation of blind pouch of vagina.👇
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| image source:ScienceDirect.com |
- Ovaries are formed because of presence of genital ridge.
- secondary sexual characters also are developed👉because of normal pituitary functioning.
- pituitary👉FSH and LH👉act upon ovaries👉release hormones👉estrogen and progesterone 👉normal secondary sexual characters.
- Mullerian agenesis +renal anomaly +skeletal anomaly👉MRKH syndrome.
- in MRKH ,genotype is normal female genotype.
- symptoms : Amenorrhea,pain during sexual discourse
- treatment:surrogacy and vaginoplasty.
- Banana shaped
- one Mullerian duct forms the complete structure.
- what happens to other Mullerian duct?
- either does not form any structure OR forms non-communicating horn
- Non Communicating horn :FUNCTIONAL AND NON FUNCTIONAL
- FUNCTIONAL :after puberty and during periods 👉growth of endometrium👉blood and endometrial lining deposited inside👉very painful during periods
- NON FUNCTIONAL :no endometrial growth
- Pregnancy👉susceptible to miscarriages and ectopic pregnancies
heart shaped uterus
- incomplete fusion of MULLERIAN DUCTS.
- pregnancy👉baby in transverse or breach position.
- only caesarean can be done and not the normal delivery.
- distance between two horns ≥ 4cm
- angle between two horns ≥ 60 degrees
UTERUS DIDELPHYS
- two Mullerian ducts do not fuse
- each Mullerian duct forms its own complete reproductive structure.
- two types :UNICOLLIS and BICOLLIS
- UNICOLLIS :both the reproductive structures have common vaginal opening .Remember : two uterus 👉 not fused.
- BICOLLIS : each reproductive system has its own vagina
NOTE: space for development of baby very small...
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| image source : inviTRA |
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| image source ; Cleveland Clinic |






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